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Hepato-pancreato-biliary and Transplant Surgery

The department specializes in treating benign and malignant diseases of the liver, pancreas, gallbladder and bile ducts. Our experienced team of surgeons is adept at performing complex operations of the liver, pancreas, bile duct and gallbladder. Besides providing cutting-edge surgical services to our local population, we are also the regional referral center as well as a leading center of clinical research.

Diseases especially cancers of the liver, pancreas, gallbladder and bile ducts are relatively common and frequently require surgery for complete recovery and good long-term outcome. Surgery usually offers the only chance of cure for HPB cancers. Surgery for these cancers is frequently technically demanding complex major operations associated with significant risks. These operations are best performed in a highly specialized tertiary center which performs a large number of these surgeries. Numerous publications in the medical literature have repeatedly demonstrated that the best patient outcomes are obtained when these procedures are conducted in a center performing a high volume of such complex cases.

Since 2000, our surgeons have performed thousands of complex liver, biliary and pancreatic resections with surgical outcomes on par with the very best centers world-wide. Our surgical results have been published in numerous world-renowned peer-review medical journals such as Annals of Surgery and Archives of Surgery. We are presently a major tertiary referral HPB center for the country and region.


Members of our department are actively involved in performing liver and pancreas transplantation operations and are experienced in all technical aspects of transplantation including deceased donor and living donor liver transplants. Liver transplantation is indicated in selected patients with severe chronic liver disease or liver cirrhosis. This procedure is also the treatment of choice in selected patients with primary liver cancers.

Pancreas transplantation is a newly available treatment modality for Type 1 diabetics in Singapore. It has been proven to be an extremely effective treatment modality for the disease and frequently may be curative. For further details on transplantation click here.

Minimally-invasive (laparoscopic)

Over the past few years, the HPB service has also adopted minimally-invasive approaches (laparoscopic surgery) for selected patients requiring liver or pancreatic resections allowing these patients to enjoy the benefits of 'key-hole' surgery. These include smaller incisions, diminished pain, early mobilization and shorter hospital stay.

As of 2014, we have performed more than 250 laparoscopic liver and pancreatic operations. We are highly competent in all minimally-invasive approaches including: pure laparoscopic, single incision laparoscopic surgery (SILS), hand-assisted laparoscopy, laparoscopic-assisted and robotic surgery.

The department also performs general laparoscopic surgery such as appendicectomies, cholecystectomies, splenectomies and adrenalectomies.

Robotic surgery (Da Vinci Robot)

The most significant advance in laparoscopy in the last 10 years is the advent of robotic laparoscopic surgery using specialized systems such as the Da Vinci Surgical Robot. Since its approval by the USFDA in 2000, it has revolutionized intra-abdominal surgery. Key attributes such as the high-resolution 3-dimensional images, presence of a tremor filter, the ability to scale motions and the use of highly dexterous articulated instruments that provide 7 degrees of motion similar to a human wrist. This allows complex manouevres, such as laparoscopic suturing in extremely small spaces or lymph node dissection along major vessels, to be performed with relative ease.

Although robotic surgery has been widely applied to urological and gynecological procedures, its use in HPB surgery world-wide remains limited. We are the pioneers of robotic surgery for pancreatic and liver resections in the country and region and our surgeons are Da Vinci accredited console surgeons.

Complex major operations including vascular resection and reconstruction

Frequently, complete surgical resection remains the only chance of cure in patients with HPB malignancies. However, these cancers are commonly deemed unresectable due to involvement of major vasculature. Utilizing surgical techniques from transplantation, our surgeons are experienced in performing complex vascular resections and reconstructions for otherwise inoperable malignancies. These technically complex surgeries are best performed in high-volume experienced tertiary centers such as ours.

Multidisciplinary approach

The HPB department works closely with the Gastroenterology & Hepatology, Nuclear Medicine, Medical Oncology and Radiation Oncology units at SGH and NCC Singapore. This is because HPB malignancies frequently require multispecialty treatment. Complex cases are discussed at weekly multidisciplinary meetings in order to determine the best treatment approach for patients and allow our patients access to the full repertoire of currently available treatment modalities.


Our department is involved heavily in clinical and basic science research with more than 200 scientific publications over the past 10 years. We are also not only heavily involved but is spear-heading numerous international multi-center clinical trials treating patients with HPB malignancies. This allows our patients to gain access to the latest and costliest cancer treatments which would otherwise not be available and frequently at no additional cost. 


Staff MembersSub-Specialty
Head & Senior Consultant
Dr Chan Chung Yip MBBS, M Med (Surg), FRCSEd (Gen)Hepatobiliary, Pancreatic, General Surgery & Liver Transplant
Senior Consultant
Prof Chung Yaw Fui, Alexander MBBS (Singapore), FRCS (Edin)Hepatobiliary, Pancreatic, Laparoscopic & General Surgery
Prof London Lucien Ooi MBBS, FCSHK (Hon), FRCS (Edin), FRCS (Glasg), MD, ProfessorHepatobiliary, Pancreatic, Laparoscopic & General Surgery, Surgical Oncology
Assoc Prof Brian Goh Kim Poh MBBS, MRCSEd, MMed (Surg), MSc, FRCSEd, FAMSHepatobiliary and Pancreatic Surgery, Liver and Kidney Transplant, Surgical Oncology and Laparoscopic / Robotic Surgery
Assoc Prof Cheow Peng Chung MBBS, M Med (Surg), FRCS (Ed), FAMSHepatobiliary, Pancreatic, General Surgery & Liver Transplant
Dr Jeyaraj Premaraj MBBS, M Med (Surgery), FRCS (Glasgow), FRCS (Ed), FAMSHepatobiliary, Pancreatic, General Surgery & Liver Transplant
Dr Mack On Pui, Peter MBBS, FRCS (Edin & Glasg), PhD, FAMS, MHlthEcon, M Med (Dundee), MBAHepatobiliary, Pancreatic, Laparoscopic & General Surgery, Surgical Oncology
Assoc Prof Lee Ser Yee MBBS, M Med (Surgery), M Sc, FRCS (Edinburgh), FAMS, FRCS(Ed)Hepatobiliary and Pancreatic Surgery, Liver Transplantation, Laparoscopic Surgery and Surgical Oncology
Dr Teo Jin Yao MBBS, MRCS (Ed), M Med (Surg), FRCS (Ed)Hepatobiliary and Pancreatic Surgery, General Surgery
Associate Consultant
Dr Tan Ek Khoon MBBSGeneral Surgery


To make or change appointment:


Department Office:

Academia Level 5
Tel: 6326 5564
(for departmental matters only)

Centre of Digestive and Liver Disease:

Block 3 Basement 1
Tel: 6321 4320

Last Modified Date :15 Aug 2017