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Speakers

DAY 1 SPEAKERS – 23 OCT 2018

CLINICAL TISSUE ENGINEERING TRACK

Prof Wayne Morrison
Keynote Speaker for Special Lecture (Open Invitation to All)
O’Brien Institute
St. Vincent’s Hospital Melbourne

Professor Wayne Morrison is the innovator of a new concept of Tissue Engineering in vivo. By combining his skills as a microsurgeon with ‘in vivo cell culture’, he has succeeded in generating tissue components as complex as cardiac muscle with a potential for use in reconstructive surgery. As an internationally renowned microsurgeon, he has led the Department of Plastic and Reconstructive Surgery at St Vincent's Hospital, Melbourne and was formerly the Hugh Devine Professor of Surgery, University of Melbourne and Director of the O’Brien Institute - an independent plastic surgical research institute now amalgamated with St Vincent’s Institute.  He continues to lead a group of scientists and clinicians involved in basic research related to Tissue Engineering. His special interest is Adipogenesis, the study of fat tissue growth.

He is co-author of the book “Reconstructive Microsurgery” and has contributed multiple chapters and written more than 300 articles. He has been the recipient of several millions of dollars in grant funding including multiple NH&MRC, government, and philanthropic grants. He has been president of international and national societies of Hand and of Microsurgery. He is a recipient of the John Mitchell Crouch scholarship, the Tattersalls award for excellence, the Sims travelling professor (Royal College of Surgeons), the B.K. Rank Professorship for the Australian Society of Plastic Surgery, Joseph Murray honorary Harvard Professor, Buncke lecturer American Society of Microsurgery, the Prince Henry’s Medal (Royal Australian College of Surgeons) and the Dieffenbach medal (German speaking societies of Surgery). He has been awarded with honorary fellowships, memberships and named lectures. 

Professor Morrison was awarded an AM in 2000, Medal of Excellence by the Australasian Soc. for Head and Neck Surgery in 2014 and in 2016 was nominated “Pioneer of Hand Surgery” by the International Federation of Societies for Surgery of the Hand (IFSSH).

A/Prof Chew Sing Yian
Invited speaker for Day 1
Associate Professor, Lee Kong Chian School of Medicine (LKCMedicine)
Associate Professor, School of Chemical and Biomedical Engineering (SCBE), Nanyang Technological University (NTU)

Sing Yian CHEW is an Associate Professor at the Lee Kong Chian School of Medicine (LKCMedicine) and the School of Chemical & Biomedical Engineering (SCBE), Nanyang Technological University (NTU), Singapore. She obtained her PhD at Johns Hopkins University in 2006, under the sponsorship of the NTU Overseas Scholarship. Thereafter, she joined SCBE as Assistant Professor later in the same year. In 2012, A/Prof Chew received her tenure and was promoted to Associate Professor in SCBE. In March 2014, Dr. Chew received joint appointment with LKCMedicine. From 2014 to 2017, she served as Associate Chair of Research & Graudate Studies in SCBE.

Dr. Chew is known for her contributions to the field of regenerative medicine and stem cell engineering. Her research interests lie in understanding the combined effects of nanotopography and biochemical signalling in directing cell fate. Specifically, her lab engineers nanofiber platforms for long-term delivery of biochemicals. Currently, Dr. Chew’s work focuses on scaffold-mediated delivery of small non-coding RNAs for long-term gene silencing applications. These biofunctional platforms are used for understanding and directing neural tissue regeneration post-traumatic injuries, stem cell fate and host-implant integration.

Since joining NTU, Dr. Chew has continued to embark on scientific learning and exchanges by serving as visiting scholar/professor to Johns Hopkins University, University of Edinburgh, INSERM (U698 and U791); University of Paris 13; University of Nantes; Jinan University in Guangzhou, China; Wyss Institute at Harvard. She also serves as the editorial board member in Drug Delivery and Translational Research, an official journal of the highly regarded Controlled Release Society. Her professional experience also includes evaluating research grants for local and international funding bodies including the Research Grant Council of Hong Kong.

Dr. Chew will be presenting her work on 'Biomimicking platforms for understanding the roles of extracellular matrix topography and biochemical signaling on neural cell fate'. Nanofibers closely imitate the size-scale and architecture of the natural extracellular matrix. These constructs represent a unique class of materials in regenerative medicine and non-viral drug/gene delivery. Fibrous topography can direct cell fate. Combined with the incorporation of gene silencing molecules, such as small non-coding RNAs, these scaffolds provide synergistic topographical and biochemical cues to cells. Here, Dr. Chew will present her team's recent findings on the roles of fiber mediated mechanotransduction and gene silencing on oligodendrocyte progenitor cell fate and myelination, in vitro and in vivo, using spinal cord injury as a proof-of-concept. 

 

Mr Abhilash Ravishankar 
Invited speaker for Day 1
Product Manager, Bangalore Integrated System Solutions (BISS)

Mr Shivakumar Narayanaswamy 
Invited speaker for Day 1
Product Support Manager EM Marketing,  Instron

The study of novel biomaterials and tissue-engineered products remains at the forefront of research around the world. Hard tissues such as bone, dentin, and enamel; soft tissues such as tendons, ligaments, skin, muscles, and arteries are all examples of tissue engineered materials or biomaterials. These materials require mechanical testing, often in an environment to mimic physiological conditions to understand and characterize force and displacement properties. Similarly, Implantable devices take many forms from cardiovascular, endovascular, neurovascular stenting and associated delivery systems to heart valves and pacemakers, through to auditory and ocular implants, such as intraocular or contact lenses. Mechanical testing takes many forms, from static tensile or compressive testing of the constituent metals and alloys, compression or flexural testing of complete devices, through to fatigue of stent materials and dynamic simulation of pressure pulsation. 
 
Instron is the leading, global supplier of mechanical testing systems, suitable for tension, compression, flexure, peel, tear, friction, torsion, and fatigue tests. Hospital and surgical products are often consumable and designed for one-time patient use. Items such as catheters, guidewires, intravenous lines, tubing, and an assortment of wound closure products such as bandages, sutures, and staples all fall within this category. Mechanical testing of these products is especially important to guarantee properties such as adequate tensile strength, low frictional forces, and sufficient elongation are appropriately matched to the application. If these mechanical characteristics are inappropriately matched for the product, patient, or surgical application, this could have disastrous effects to the patient. 

Industry experts - Mr Abhilash Ravishankar and Mr Shivakumar Narayanaswamy - will be presenting about 'Static Testing Solutions: Medical Devices & Biomaterials'. Their presentation covers topics such as the structural and viscoelastic properties of biomaterials, monotonic testing of hard & soft tissues, challenges associated with hard & soft tissue testing, static bio-specific products and software & service(s). 

 

DAY 2 SPEAKERS – 24 OCT 2018

BIOMECHANICS TRACK

Prof Lim Beng Hai
Keynote speaker for Day 2
Director and Consultant Hand Surgeon, Centre for Hand And Reconstructive MicroSurgery (CHARMS)

Dr Lim obtained his basic medical degree from the National University of Singapore in 1985. He obtained his Master of Medicine (Surgery) Singapore and the Fellow Royal College of Surgeons (Edinburgh) in 1990. He was accredited as a Specialist in Hand Surgery in September 1998. Dr Lim did his fellowship in Hand and Reconstructive Microsurgery at the Christine Kleinert Institute for Hand and Microsurgery in 1994 and was awarded the prestigious Senior Fellowship in Hand Surgery by the University of Louisville Hospitals in 1995 to 1996. 

Upon his return to Singapore, he was appointed an Adjunct Assistant Professor position to the Department of Surgery, University of Louisville, USA. Dr Lim served as a consultant Hand Surgeon at the Singapore General Hospital until 2000 June where he was appointed Chief to the Department of Hand and Reconstructive Microsurgery at the National University Hospital (NUH).

While in NUH, he participated actively in the management of the hospital. He was Associate Chairman Medical Board in 2001/2002 and Vice Chairman Medical Board 2003/2004. He holds the Associate Professor position in the Department of Orthopaedic Surgery, in NUS and heads the Hand Division in the department. He continues to be an Adjunct Associate Professor to the department until 2011.

He enjoys teaching undergraduate and postgraduate students. He set up the Microsurgical Training Laboratory in NUH in 2001 and was Program Director for the laboratory and started joint training program in microsurgery with Aesculap Academy in 2003. The success of the Microsurgical Training Laboratory propelled him to set up the STAR (Skills, Training And Research) Laboratory in NUH in 2003 The STAR lab was further expanded to include Digital Medicine Laboratory.

As the Chief to the Department of Hand and Reconstructive Microsurgery, he started the Department's annual cadaveric symposium and workshop for General Practitioners in 2000 and in 2001 the Foundations in Musculoskeletal Surgery for advanced trainees in Hand, Plastics and Orthopaedic surgery.

His research interests include Wrist Instabilities - Scapholunate and Distal Radial Ulnar Joint instabilities, Flexor tendon repairs and training and certification in microsurgery. Widely published and some of his innovative surgical techniques are recognized by the international Hand Surgery community. Some of the techniques were cited in texts like the Green's Operative Hand Surgery, Atlas of Hand Clinics and Grabb's Encyclopedia for Flap Surgery. 

A/Prof Zhong Liang
Invited speaker for Day 2
Principal Investigator,  National Heart Centre Singapore (NHCS)
Associate Professor, Duke-NUS Medical School 

Assoc Professor Zhong Liang is Principal Investigator at the National Heart Centre Singapore (NHCS) and Associate Professor at Duke-NUS Medical School. He heads Cardiovascular Bioengineering Theme, Cardiovascular Image Processing Lab and Computational Cardiology Lab.  

Assoc Professor Zhong has interest in the cardiovascular biomechanics, non-invasive cardiac imaging, and coronary circulation in health and disease, and translational research. He has published more than 100 peer-reviewed articles in international journals, 18 book chapters. His research has received several national and international awards from Singapore Cardiac Society (2011 and 2012), Asean Federation of Cardiology (2012), APPCS & APSACH (2011), APPCSS (2012), Academy of Medicine Singapore (2013) and Medical Research SingHealth group (2014). Dr. Zhong is the chairman of Engineering in Medicine and Biology Society (EMBS) Singapore Chapter, committee member of ISMRM Singapore Chapter and member of European Society of Cardiology. Currently, he has led in the development of non-invasive fractional flow reserve from computed tomography coronary angiography (CTCA) and computational fluid dynamics (CFD) in coronary artery disease (NCT03054324) and INITIATE multicentre study in congenital hear disease (NCT03217240).

Assoc Professor Zhong will be speaking about Computational Fluid Dynamics in Cardiovascular Applications. Computer modeling and simulation (i.e. computational fluid dynamics) is emerging as a defined program in the development of or regulatory evaluation of a medical product and medical intervention. The growth in science and technology has catalysed to develop the high-tech products. These advances require engineers capable of intimate interdisciplinary collaboration, particularly with physicians at each stage of research.

For example, the use of mathematical methods in medicine enjoyed its most signal successes in the application of invasive fractional flow reserve (FFR), and latterly non-invasive FFR derived from computed tomography (FFR-CT) by combining cardiac imaging and computational fluid dynamics (CFD). FFR-CT is now FDA approved (HeartFlow®), and has recently been demonstrated to be clinically useful for angina management in the PLATFORM trial. This talk will cover the basic of the cardiovascular biomechanics, scientific basis of computational fluid dynamics of FFR-CT and its application in patients with suspected coronary artery disease. 

A/Prof Desmond Chong
Invited speaker for Day 2
Associate Professor, Engineering Cluster, Singapore Institute of Technology (SIT)

Dr Desmond Chong is currently an Associate Professor with the Engineering Cluster of Singapore Institute of Technology. He received his BEng and MEng (by research) in Mechanical Engineering from Nanyang Technological University, and a PhD in Biomechanics from Imperial College London. His research interests are in the areas of orthopaedic and musculoskeletal biomechanics, finite element analysis and experimentation, medical devices design (joint implants and rehabilitation), and gait and human motion analyses. He is an active member of the American Society of Mechanical Engineers (ASME), and currently serves as the Chair of the ASME Singapore Section and International Sections Representative of the ASME Group Engagement Committee.

Biomechanics is the science that studies the effects of forces on biological tissues, organs and systems, in relation to biological and medical problems. In orthopaedic applications, biomechanics concepts are employed to enhance the understanding of the mechanical behaviour of total joint replacements (TJR). Long-term survivorship of TJRs relies on the strength of bone around the implant and its initial stability. Aseptic component loosening caused by mechanical factors is a recognised failure mode for joint prostheses. Bone resorption (remodelling) due to “stress-shielding” of the stiff stemmed implants will potentially lead to weakened bone strength, and presents a challenge for revision surgery. This presentation will cover the basics of orthopaedic biomechanics, and the use of patient-specific finite element analysis (FEA) and in-vitro cadaveric study for the investigation of fixation performance of TJRs and prosthetic design requirements.

Dr Daniel Seng
Invited speaker for Day 2
Senior Resident, Department of Orthopaedic Surgery, National Healthcare Group (NHG)

Dr Daniel Seng is a senior resident in the National Health Group orthopaedic surgery residency program. He obtained his medical degree in the University of Aberdeen (United Kingdom) in 2011 and is a Member of the Royal College of Physicians and Surgeons of Glasgow since 2014. He received the award of outstanding junior resident in 2017 and outstanding senior resident in 2018. Dr Seng has a special interest in biomechanics research in Orthopaedics. He has several on-going research projects in biomechanics with Nanyang Technological University of Singapore.

Mr Ong Chi Wei
Invited speaker for Day 2
PhD Graduate Student, National University of Singapore (NUS)

Mr. Ong Chi Wei is currently doing his research works in Biofluid Mechanics lab in the National University of Singapore. He holds a Master of Engineering Science from the University of Malaya, specializing in cardiovascular modelling. His masters thesis topic is modeling the fluid structure interaction between left ventricular assist device and left ventricle of the heart. He is also a registered biomedical engineer who worked in the community hospital in Kuala Lumpur, Malaysia before joining NUS as a PhD graduate student. He has published and co-authored nine peer-reviewed articles and presented his works in numerous international conferences. His research interests are in computational and experimental biofluid mechanics. He has over five years of research expertise in the computational study of the development of various medical devices, such as stents design and left ventricular assist devices. Currently, his Ph.D. project is focusing on the hemodynamic interrogations for the novel preferential covered stent design implanted in aortic aneurysms from computational and experimental perspective. He has experienced in using software e.g. COMSOL, ANSYS, ABAQUS and also applying the particle image velocimetry for studies. Other projects he has collaborated in the various hospitals is studying the impact of stent design in the carotid artery and developing the fluid structure interaction framework to model the interaction between the synovial fluid and wrist bone.

DAY 2 PANELISTS & MODERATOR– 24 OCT 2018


Prof Duncan Angus McGrouther
Panel Moderator
Senior Consultant, Department of Hand Surgery, Singapore General Hospital (SGH)
Director, Biomechanics Lab, Singapore General Hospital

Professor Duncan Angus McGrouther is a Senior Consultant at the Department of Hand Surgery in Singapore General Hospital (SGH). He is also the Director of SGH Biomechanics Laboratory, an appointed Adjunct Professor at Duke-NUS Medical School and an Honorary Professor of University of Manchester. He formerly held Consultant Plastic Surgeon Positions in the UK since 1979, and two Full University Professorial Posts in University College London from 1989 to 2001 and University of Manchester from 2001 to 2013. Trained in the United Kingdom and Germany, he has a medical research Doctorate and also a Masters degree in Bioengineering.

In addition to clinical practice, Professor McGrouther is dedicated to laboratory research and clinical trials. His research interests are in the areas of tissue engineering and mechanotransduction. He has established wet laboratories and employed research staff, including postdoctoral research scientists from biological sciences and engineering, and trained medical undergraduate and postgraduate students in scientific methodology. He has co-authored several books, including “Principles of Hand Surgery” and “Microvascular Surgery and Free Tissue Transfer”, published over 200 articles and served as Editor for numerous journals in Plastic Surgery, Wound Healing and Tissue Engineering and a speaker for over 1000 international seminars, lectures and conferences. He also co-founded The Healing Foundation – a charity funding for wound healing research that has raised over 50 million pounds to date. He currently holds two grants as Principal Investigator: SGH-SUTD developing 3D Ultrasound imaging, SGH-NTU developing synthetic peripheral nerve conduits.

Professor McGrouther’s personal honours include a Wolfson-Royal Society personal merit award, and election to Fellowship of the Academy of Medical Sciences. He has also been a Council Member and Trustee of the Royal College of Surgeons of England, in which he authored the strategy for postgraduate surgical education, and the College’s undergraduate surgical curriculum. Currently, he continues to support the development of the academic base in the hospital setting with a particular focus on building activity between musculoskeletal clinical practice and the basic science base available in the universities.

A/Prof Jodhbir Mehta
Panelist for Day 2
Head & Senior Consultant, Corneal & External Eye Disease Service, 
Singapore National Eye Centre (SNEC)

A/Prof Zhong Liang
Panelist for Day 2
Principal Investigator, National Heart Centre Singapore (NHCS)
Associate Professor, Duke-NUS Medical School 

 

A/Prof Desmond Chong
Panelist for Day 2
Associate Professor, Engineering Cluster,
Singapore Institute of Technology (SIT)

 

More speakers and panelists details to be released soon!

1st International Biomechanics & Clinical Tissue Engineering Symposium 2018, 23rd - 24th October 2018, Singapore
Add: 20 College Road, Academia, Level 1: Seminar Room L1-S2, Singapore 169856
Tel: +65 6576 7962 | Email: biomechanics.lab@sgh.com.sg

Last Modified Date :18 Oct 2018